Different ways of protein transport.

Heyo homiees..
Protein transportation is the topic of discussion for today.

To understand the general principles by which sorting signals operate, it is important to distinguish three fundamentally different ways by which proteins move from one compartment to another.

GATED TRANSPORT:

The protein traffic between the cytosol and nucleus occurs between topologically equivalent spaces, which are in continuity through the nuclear pore complexes.

VESICULAR TRANSPORT:

Membrane-enclosed transport intermediates which may be small, spherical transport vesicles or larger, irregularly shaped organelle fragments ferry proteins from one compartment to another. The vesicles load with the contents that are supposed to be transported from the donor compartment. Then the vesicles separate and travel via cytosol to the target compartment and merge with them thus transporting the contents within.

TRANSMEMBRANE TRANSPORT:

Membrane-bound protein translocators directly transport specific proteins across a membrane from the cytosol into a space that is topologically distinct. The transported protein molecule usually must unfold to snake through the translocator. This type of transport usually occurs between cytosol and mitchondrion or ER lumen.

Thus these are the three ways for protein transport. Further protein sorting will be discussed later.

Hope this helps.

Thanks a lot.

-Staph.