Thursday 2 July 2015

Ultimate Enzyme classification

Hello Everyone..
A lot of times when I am studying enzymes, I get confused with their names and functions in any particular reaction. Hence I have tried to classify them based on what reactions they carry out. You will encounter these enzymes in your reactions and biochemical pathways. Their names might get altered depending on the substrates or the intermediates produced. But the category remains the same.

So here's an Ultimate Enzyme Classification :D


  1. Kinases: These enzymes are seen everywhere when there is an addition of ATP in any reactions.
  2. Oxidoreductases: Transfer of electrons (hydride ions or H atoms).
  3. Dehydrogenases: Removal of Hydrogen groups.
  4. Hydrolases:  Hydrolysis reactions (transfer of functional groups to water).
  5. Ligases: Formation of C-C, C-S, C-O, and C-N bonds by condensation reactions coupled to ATP cleavage.(Mostly seen in DNA replication)
  6. Transferases: Group transfer reactions.(eg. Phosphotranferases)
  7. Lyases: Addition of groups to double bonds, or formation of double bonds by removal of groups.
  8. Isomerases and Epimerases: Transfer of groups within molecules to yield isomeric forms.(eg.Ribulose-5-PO4 isomerase and Ribulose-5-PO4 Epimerase in HMP Pathway).
I guess most of the enzymes that we notice in biochemistry come under these classes. Therefore, now you are not in problem if you forget your enzymes in your exams. Just write it's name based on the reaction and combine it with the substrate name and according to me you will be 99% correct. 

For eg. Ribulose-5-phosphate isomerase is the enzymes responsible for conversion of Ribulose-5-PO4 to Ribose-5-PO4. 



This way you are not losing much of your marks  :D

Hope it helps you all.

Lots of Love

-Staph.

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